The Science Behind Our Products
We value research. We seek new scientific advancements in both the discovery of new ingredients and further research into the ingredients we already use. This research allows us to deliver products of the highest quality to our customers.
These are the scientific publications we have been involved in:
Author: Miho Yoshida, Yamakawa, Kazuyuki Uchino, Yasuhiro Watanabe, Tadashi Adachi, Mami Nakanishi, Hikari Ichino, Kunihiro Hongo, Tomohiro Mizobata, Saori Kobayashi, Kenji Nakashima, Yasushi Kawata
Journal: Nutritional Neuroscience
Year: in press
Volume, Issue, Page: in press
Summary: Alzheimer's disease is caused by aggregation of amyloid beta peptide. This study revealed that anthocyanoside extracts obtained from bilberry on the in vitro progression of amyloid beta peptide fibril formation in vivo.
Author: Tomoya Asano, Saori Kobayashi, Katsuhisa Sakano, Shukuko Ebihara
Journal: Japanese Journal of Medicine and Pharmaceutical Science
Volume, Issue, Page: 72, 7, 1261-1273
Summary: Most women are interested in skin health and beauty. Resveratrol extracted from lingonberry is well-known as an antioxidant. Supplement made from this extract improved skin elasticity in women.
Author: Norihiro Nagai, Kanako Izumi-Nagai, Misa Suzuki, Hajime Shinoda, Takashi Koto, Atsuro Uchida, Hiroshi Mochimaru, Yohei Tomita, Seiji Miyake, Saori Kobayashi, Mariko Sasaki, Kazuo Tsubota, Yoko Ozawa
Volume, Issue, Page: 35, 4, 820-6
Summary: Lutein and Zeaxanthin intake are correlated to macular pigment optical density (MPOD). MPOD was positively correlated with serum concentrations of L and Z and dietary L intake and inversely correlated with serum oxidized low-density lipoprotein.
Author: Y. Ozawa, M. Kawashima, S. Inoue, E. Inagaki, A. Suzuki, E. Ooe, S. Kobayashi, Kazuo Tsubota
Journal: The journal of nutrition, health & aging
Volume, Issue, Page: 19, 5, 548-554
Summary: To examine the effect of a dietary supplement containing bilberry extract on eye fatigue, the acute video display terminal (VDT) loads were used in this study. VDT load-induced ocular fatigue sensation, ocular pain, eye heaviness, uncomfortable sensation, and foreign body sensation were mitigated more in the BE group than in the control group at 8 week.
Author: Kenjirou Ogawa, Yoshiki Kuse, Kazuhiro Tsuruma, Saori Kobayashi, Masamitsu Shimazaw, Hideaki Hara
Journal: BMC Complementary and Alternative Medicine
Volume, Issue, Page: 14, 120
Summary: Bilberry and lingonberry contain high amounts of polyphenols and thus confer health benefits. Bilberry and lingonberry extracts exert protective effects against blue LED light-induced retinal photoreceptor cell damage mainly through inhibition of ROS production and activation of pro-apoptotic proteins.
Author: Seiji Miyake, Saori Kobayashi, Kazuo Tsubota, Yoko Ozawa
Journal: Biochemical and Biophysical Research Communications
Volume, Issue, Page: 446, 2, 535–540
Summary: Lutein treatment of a neuronal cell line (PC12D) immediately resulted in reduced intracellular ROS levels, implying that it has a direct role in ROS scavenging. Lutein treatment also induced phase II antioxidative enzyme expression, probably via a nuclear factor-like 2 independent pathway.